Recommendations and practices to optimize stroke therapy: developing effective translational research programs.
نویسنده
چکیده
منابع مشابه
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Stroke is an enormous public health problem with an imperative need for more effective therapy. Recombinant tissue plasminogen activator is the only licensed drug for acute stroke, but its efficacy may be limited by the toxicity of the compound and by reperfusion injury. The coadministration of neuroprotective drugs could augment the value of thrombolytic therapy, but the evidence in support of...
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Translational stroke research is a challenging task that needs long term team work of the stroke research community. Highly reproducible stroke models with excellent outcome consistence are essential for obtaining useful data from preclinical stroke trials as well as for improving inter-lab comparability. However, our review of literature shows that the infarct variation coefficient of commonly...
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ورودعنوان ژورنال:
- Stroke
دوره 44 3 شماره
صفحات -
تاریخ انتشار 2013